WU-LM1

Key persons involved

Michiel Kleerebezem, PhD, has had a leading role in several national and international projects focused on functional (meta-)genomics of bacteria residing in the GIT and the host-microbe interactions. Since 1995 he is associated with NIZO food research and was awarded the special academic chair of Bacterial Metagenomics at Wageningen University in 2007, and has since 2011 joined the Host Microbe Interactomics group at the same university. He was awarded the mid-career senior scientist stimulation award by LABIP in 2005. He is (co)authored on more than 175 publications and co-inventor on more than 20 patent applications.

3 key publications

  • Bron PA, van Baarlen P, Kleerebezem M. Emerging molecular insights into the interaction between probiotics and the host intestinal mucosa. Nat Rev Microbiol. 2012, in press. [Pubmed]
  • van Baarlen P, Troost F, van der Meer C, Hooiveld G, Boekschoten M, Brummer RJ, Kleerebezem M. Human mucosal in vivo transcriptome responses to three lactobacilli indicate how probiotics may modulate human cellular pathways. Proc Natl Acad Sci U S A. 2011 Mar 15;108 Suppl 1:4562-9.[Pubmed]
  • Marco ML, de Vries MC, Wels M, Molenaar D, Mangell P, Ahrne S, de Vos WM, Vaughan EE, Kleerebezem M. (2010) Convergence in probiotic Lactobacillus gut-adaptive responses in humans and mice. ISME J. 4:1481-1484. [Pubmed]